Find Out Is Leaky Gut Real
And the Zonulin, Intestinal Hyperpermeability Connection
Is leaky gut real? Yes, this is used to describe the condition of “Intestinal Hyperpermeability“, a fancy medical term that means the intestinal lining has become more porous with more holes developing that are larger in size and the screening out process is no longer functioning properly. The fallout results in larger, undigested food molecules and other “bad stuff”(yeast, toxins, and all other forms of waste) that your body normally doesn’t allow through, to flow freely into your bloodstream.
Leaky gut Syndrome is a real medical phenomenum. Why, it has a lot of relating symptoms with other digestive disorders. Many of these digestive abnormalities have inflammation of the intestine. This is one problem. The second is an unbalance bacterial flora. When intestinal bacteria is dysregulated. More invasive kinds come into play; aggressive bacteria, fungus, viruses and infections.
There are many diseases that are linked to permeable intestinal wall, reasons why. It’s become more relavent that our immune system and central nervous system has a huge job in and on or digestive system especially the intestinal tract.
The problem with permeable intestinal wall used in a medical criteria. It plagues people in categorizing this term with it’s own focused set of symptoms or complications. This syndrome has a long list of symptoms that are similar and exactly the same as many digestive disorders and even diseases outside the digestive tract. There is much evidence that proves that are well regulated junctions of the intestinal wall can be disregulated, worned out, like with the case of celiac disease patients and autoimmune sufferers. Weaked the opening and closing of the junctions in the intestinal tract to a near complete halt.
Intestinal Hyperpermeability and Gut-Brain Axis
Scientist recently have come a long way to find out that the gut does have a connection to your brain. They have discovered a complex communication system. If the intestinal microbiota (bacteria in the intestine) is in poor health, so will your brain. Your health is correlated with this newly discovered syncronicty of the brain and gut.
They have proven the microbiota has a impact to the Gut-Brain axis, not just the permeability aspect of the intestinal.
The bowels is connected to the central nervous system and specifically the enteric nervous system. This is how it connects to the brain. There are links with this nervous system that sync up into our emotional and cognitive centers of the brain with peripheral intestinal functions.
These explains why people with anxiety, depression, autism, and other neurallogical disorders. Also have some weakening of their immune system, microbiota, and permeable intestinal wall. This study is in the US National Library of Medicine National Institutes of Health.
Most of the body’s immune system is in the bowels, so pathology and dysfunction in the intestine and imbalanced intestinal flora can cause neuroinflammation and possibly even neurodegenerative disease overtime.
Intestinal Wall and Zonulin
Zonulin is a key player to leaky gut syndrome. Why, zonulin is a protein that opens the tight junctions of the intestinal wall.
Alessio Fasano said, certain genetics, both intestinal and extraintestinal autoimmune, inflammatory, and neoplastic disorders can untune the zonulin mechanism.
Who is Alessio Fasano
Who is Alessio Fasano. Hi is a M.D. from Italy. He is pediatric gastroenterologists and a longtime researcher. He holds many positions:
- W. Allan Walker Chair in Pediatric Gastroenterology and Nutrition
- Division Chief, Pediatric Gastroenterology and Nutrition; Director, Center for Celiac Research and Treatment
- Director, Mucosal Immunology and Biology Research Center; Associate Chief for Basic, Clinical and Translational Research
- Founder of Massachusetts General Hospital’s Center for Celiac Research, His research and on going development in the science of Celiac and all things about gluten interaction to our gastrointestinal tract (gluten related disorders).
Dr. Alessio Fasano is specialized in treating all sorts of gluten related disorders, at any age. His treatments includes celiac disease, wheat allergy, and gluten sensitivity. He also treats harder to mend diseases related to the bowels like Chronic diarrhea that other doctors are not yet up to par with his skill level and research.
He has a great book Called Gluten Freedom: The Nation’s Leading Expert Offers the Essential Guide to a Healthy, Gluten-Free Lifestyle. He discusses how the latest scientific research and treatments in his book. He discusses what to do if you have gluten issues or gastrointestinal issues that may be a link to gluten.
He also has lots of discoveries of how our intestinal tract can influence our brain to mild brain symptoms, like occassional headaches, foggy mind and all the way to depression, anxiety and autism. As will, his book describes what you can do at your home today to start combating for your self from gastrointestinal issues.
The Discovery of Zonulin
Since the Discovery of zonulin in the year 2000. This protein has a very special job. It’s responsibility is in the regulation of the tight junction. It will open just enough where it can only let out fully digestable food particles into the blood stream.
A second component to this discovery. Real researchers from the University of Maryland School of Medicine. The zonulin protein regulator for your intestinal wall can be untuned by wheat. Wheat containing the gluten, has two components. One of them is gliadin. This glicolin has been found to untuned the regulation of zonulin. Allowing the pathway to open up wider then it should be.
Here’s a study of a significant revelation proven on what zonulin can do with sick patients. Giovanni Barbara and a team of researchers at the University of Bologna. Have conducted a study composed of four groups. To measure levels in the blood. These groups people with celiac disease, irritable bowel syndrome, gluten sensitive people and healthy individuals. The groups of celiac and gluten sensitivities showed unusually high levels of zonulin and where the highest in the four group study. Irritable bowel syndrome sufferers had high levels in the blood but not as high as the first two. Healthy individuals showed insignificant levels of zonulin in the blood.
Barbara presented the results at the 23rd United European Gastroenterology Week in Barcelona, Spain. This is a strong validation on credibility of leaky gut. On top that there is over 10,000 publications relating to gastrointestinal issues in the Journal of Gastroenterology.
How to Treat Leaky Gut
How to treat leaky gut, has many approaches. Finding out which is difficult but they all have some similarities or quite close to the same thing. I like to follow the approach of an institute of practitioners that actually find the underlying cause of gastrointestinal issues plus other diseases. This organization is called The Institute for Functional Medicine.
These practioners do not succumb to the normal medical approach. Rather they treat the whole patients body entirely. Not just isolating the body into different sections, nor seeing every symptom as a isolated fragment. They don’t stay within the bounds of one body part and have a single treatment.
The approach to treating a permeable intestinal tract have been tried and tested by many Medical doctors, Naturopathic doctors and even chiropactors over the years. When it came down to it. By what means to handle a permeable intestinal tract and other digestive problems. The Institute of Functional Medicine have composed a method called the 4R’s program.
The 4r’s are: Remove, Replace, Reinoculate, and Repair.
- Remove: Things that need to be removed are the stuff that are irritating your intestinal tract. Things like inflammatory foods, such as gluten, wheat, diary, soy, eggs, corn and sugar. As will conventional meats. Alcohol and caffeine has to go out your life. They are irratents to your intestine. Furthermore drugs, especially antibiotics. Plus parasites and fungus infection must be removed. If your taking drugs, consultant with a physician before coming off of them.
- Replace: What needs to be replaces is with good essential component for digestion. Stomach acid , enzymes, and vitamins d and Zinc. Our use of medications like antiacids and a poor, nutritionally depleted and harmful diet. Takes the place of our nature given digestive tools.
- Reinoculate: With years of almost any assortment of medications, gluten, infections. Will deplete our bacteria allies and allow more harmful bacteria take its place. The purpose of the third R is to put back good bacteria in our gut normal levels of bacteria.
- Repair: Last but not least. Is repairing that worn out intestinal tract. With nutrients. Some of these great nutriments are vitamins like A and C. Omega 3 fish oil is good to add. Including a awesome amino acid called L-Glutamine. Which is one of the superb intestinal repair nutriments to get.
Is Leaky Gut Real
Many people have been asking is leaky gut real. As with time more and more people are going to their doctors of many specialties. Coming with them t
he same bag of health issues. Now we see researchers coming forth with evidence. A doctor who discovered how a simple plant protein can widen little junction in our gut further apart. At a excegerated level that contributes to a intestinal hyperpermeability. Furthermore a great health institution has been erected by many doctors on how to treat leaky gut. that had a more open mind to see through the heart of the problem. Because of that, they have constructed more techniques, exstensive analysaton and more natural methods to treating intestinal hyperpermeability as will as diseases. A more effective way of reverse chronic health conditions.